Pediatric Hematology and Oncology: Scientific Principles and Clinical Practice

Pediatric Hematology and Oncology Scientific Principles and Clinical PracticeBy

  • Edward J. Estlin, BSc (Hons), PhD, MRCP, FRCPCH Macmillan Consultant in Paediatric Oncology, Department of Paediatric Oncology, Royal Manchester Children’s Hospital, Manchester, UK
  • Richard J. Gilbertson, B.Med.Sci (Hons), MRCP, PhD Co-Leader, Neurobiology and Brain Tumor Program; Director, Molecular Clinical Trials Core, Departments of Developmental Neurobiology and Oncology, St Jude Children’s Research Hospital, Memphis, TN, USA
  • Robert F. Wynn, BA, MD, MRCP, FRCPath Consultant Paediatric Haematologist and Programme Director, Blood and Marrow Transplant Unit, Royal Manchester Children’s Hospital, Manchester, UK

This new textbook has an international authorship and is a practical, up-to-date resource for clinicians responsible for the care of children with oncologic and malignant hematologic disease. It is specifically designed for practicing oncologists and hematologists, pediatricians with an interest in childhood cancer and trainees seeking a systematic approach to these disorders.   This new textbook has an emphasis on the visual presentation and ease of reading of contemporary and comprehensive information for children’s cancers and contains detailed tables, fact boxes and illustrations.

The textbook begins with an introduction to the general principles of the scientific foundation and treatment of childhood cancers and hematological malignancies. Separate sections are then devoted to descriptions of central nervous system tumors, hematological malignancies and solid tumors of childhood which encompass epidemiology, cellular and molecular biology, cancer genetics, immunology, pharmacology and the findings of clinical trials. For each area of science covered, key original references and reviews are highlighted to direct further reading.

Diagnostic, biological, and therapeutic issues are integrated into each tumor-specific chapter, with evidence supporting the current rationales for risk stratification and the development of novel therapies. A final section then explores supportive care, palliative care, late effects considerations and psychosocial issues as relate to children’s cancer.

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